Mega Drive / Genesis - D
- Daffy Duck in Hollywood
- Dai Makai-Mura
- Daisenpuu
- Dangerous Seed
- Darius 2
- Dark Castle
- David Robinson's Supreme Court
- Daytona
- Daze before Christmas
- Deadly Moves
- Death and Return of Superman
- Decap Attack
- Demolition Man
- Desert Demolition
- Desert Strike
- Devil's Crush
- Devilish
- Dick Tracy
- Dino Land
- Dinosaurs for Hire
- Disney's Aladdin
- Disney's Ariel - the Little Mermaid
- Disney's TaleSpin
- Disney's the Jungle Book
- Disneys Beauty and the Beast
- Disneys Dschungelbuch
- Disneys Jungle Book
- Divine Sealing
- Doki Doki Penguin Land
- Donald Duck in Maui Mallard
- Donald Duck Starring Maui Mallard
- Donald in Maui Mallard
- Doom Troopers
- Double Dragon 3
- Double Dragon 5 - the Shadow Falls
- Double Dribble - Playoff Edition
- Dr. Robotnik's Mean Bean Machine
- Dragon Ball Z
- Dragon's Fury
- Dragon's Revenge
- Dschungelbuch
- Duke Nukem 3D
- Dune - the Battle for Arrakis
- Dune 2 - Der Kampf um Arrakis
- Dyna Brothers
- Dyna Brothers 2
- Dynamite Duke
- Dynamite Headdy