Mega Drive / Genesis - B
- B.O.B.
- Baby's Day Out
- Back to the Future - Part 3
- Back to the Future 3
- Ballz
- Ballz 3D
- Ballz!
- Bare Knuckle
- Bare Knuckle 2
- Bare Knuckle 3
- Barkley - Shut Up and Jam 2
- Bart's Nightmare
- Bass Masters Classic
- Batman
- Batman - Revenge of the Joker
- Batman Forever
- Batman Returns
- Battle Frenzy
- Battle Mania
- Battle Mania - Daiginjou
- Battle Tech
- Battlecorps
- Battletech
- Battletoads
- Battletoads / Double Dragon
- Battletoads and Double Dragon
- Beast Wrestler (Beast Warrior)
- Beauty and the Beast - Belle's Quest
- Beauty and the Beast - Roar of the Beast
- Beavis and Butthead
- Beyond Oasis
- Bill's Tomato Game
- Bio Hazard Battle
- Bio-Hazard Battle
- Bloodshot
- Blue Almanac
- Boogerman
- Bram Stoker's Dracula
- Brett Hull Hockey '95
- Brett Hull Hockey 95
- Brian Lara's Cricket
- Brutal - Paws of Fury
- Bubba 'n' Stix
- Bubsy
- Bubsy 2
- Budokan
- Bugs Bunny Double Trouble
- Bulls vs. Lakers and the NBA Playoffs
- Burning Force