Apple Macintosh - S
- S.C. Out
- Sabrina - the Teenage Witch - Spellbound
- Sacred Ground
- Safecracker
- Sam and Max Hit the Road
- Samorost 2
- Scepters
- Secret Island of Dr. Quandary
- Secret Island of Dr. Quandry
- Secret of Monkey Island
- Secret of Monkey Island - Special Edition
- Secret of the Silver Blades
- Sensory Overload
- Settlers 2
- Shadow Warrior
- Shadow Wraith
- Shattered Steel
- Sherlock - the Riddle of the Crown Jewels
- Shockwave Assault
- Shogun
- Sid Meier's Civilization
- Sid Meier's Civilization 2
- Sid Meier's Civilization 3
- Sid Meier's Civilization 4
- Sid Meier's Civilization 5
- Silver
- Sim Ant
- Sim Earth
- Sim Farm
- Sim Isle
- Sim Life
- Sim Safari
- Sim Theme Park
- Sim Tower
- Sim Town
- SimAnt
- SimCity
- SimCity (1989)
- SimCity 2000
- SimCity 3000
- SimCity 4
- SimCity Classic
- SimEarth
- SimFarm
- SimIsle
- SimLife
- Simon the Sorcerer
- Simpsons - Virtual Springfield
- Sims
- Sims - Das volle Leben
- Sims - Hokus Pokus
- Sims - Hot Date
- Sims - Megastar
- Sims - Party ohne Ende
- Sims - Tierisch gut drauf
- Sims - Urlaub total
- Sims 2
- Sims 2 - Apartment-Leben
- Sims 2 - Bon Voyage
- Sims 2 - Freizeit-Spaß
- Sims 2 - Gute Reise
- Sims 2 - Haustiere
- Sims 2 - Nightlife
- Sims 2 - Open for Business
- Sims 2 - Vier Jahreszeiten
- Sims 2 - Wilde Campus-Jahre
- Sims 3
- Sims 4
- SimSafari
- SimTown
- Sin
- Skittles
- Slithereens
- Soldier of Fortune 2
- Solid State Pinball - Crystal Caliburn
- Space Colony
- Space Madness
- Spectre
- Spectre Classic
- Spectre VR
- Spider-Man
- Spore
- SPQR - the Empire's Darkest Hour
- Spycraft - the Great Game
- Stanley Parable
- Star Trek - Klingon
- Star Trek - Klingon Honor Guard
- Star Wars - Dark Forces
- Star Wars - Droid Works
- Star Wars - Galactic Battlegrounds
- Star Wars - Jedi Knight 2 - Jedi Outcast
- Star Wars - Knights of the Old Republic
- Star Wars - Rebel Assault
- Star Wars - Rebel Assault 2
- Star Wars - X-Wing
- Starcraft
- StarCraft - Brood War
- Starcraft 2 - Wings of Liberty
- Stardust
- Starflight 2
- StaStar Trek - Voyager - Elite Force
- Stick it to the Man!
- Stunt Copter
- Summoner
- Super Wing Commander
- Superbrothers - Sword & Sworcery EP
- Superstar Chefs
- Suspect
- Swoop
- Sword of Sodan
- Syndicate
- System Shock
- System's Twilight