PSP - PlayStation Portable - S
- Saikyou Toudai Shogi Portable
- Saint Seiya Omega - Ultimate Cosmo
- Salamander Portable
- Samurai Shodown Anthology
- Samurai Warriors - State of War
- Sarugechu P!
- SBK 09
- SBK-07 Superbike World Championship
- SBK-08 Superbike World Championship
- SBK-09 Superbike World Championship
- Scarface - Money. Power. Respect
- Scarface - Money. Power. Respect.
- Scarface - the World is yours
- School Rumble - Anesan Jiken Desu!
- Scooby Doo! Who's Watching Who?
- Scrabble
- SD Gundam G Generation
- SD Gundam G Generation Portable
- SD Gundam G Generation World
- Secret Agent Clank
- Secret Saturdays - Beast of the 5th Sun
- Sega Genesis Collection
- Sega Rally (Revo)
- Sega Rally Revo
- Sengoku Basara - Battle Heroes
- Sengoku Cannon - Sengoku Ace Episode 3
- Senjou no Valkyria 3
- Shadow of Destiny
- Shaun White Snowboarding
- Shift 2 Unleashed - Need for Speed
- Shin Megami Tensei - Devil Summoner
- Shin Megami Tensei - Persona
- Shin Megami Tensei - Persona 2 - Innocent Sin
- Shin Megami Tensei - Persona 3 Portable
- Shin Sangoku Musou - 2nd Evolution
- Shin Sangoku Musou - Multi Raid
- Shining Hearts
- Shinobido - Geschichten des Ninja
- Shinobido Homura - Soul of the Ninja
- Shrek der Dritte
- Shrek Smash and Crash
- Shrek the Third
- Sid Meier's Pirates
- Sid Meier's Pirates!
- Sid Meier's Pirates! Live the Life
- Silent Hill - Origins
- Silent Hill - Shattered Memories
- Silent Hill Experience
- Silent Hill Origins
- Silverfall
- Simpsons - Das Spiel
- Simpsons Game
- Sims 2
- Sims 2 - Castaway
- Sims 2 - Gestrandet
- Sims 2 - Haustiere
- Sims 2 - Open for Business
- Sims 2 - Pets
- Skate Park City
- Smart Bomb
- Smartbomb
- Smash Court Tennis 3
- SNK Arcade Classics - Volume 1
- SNK Arcade Classics Volume 1
- SNK Arcade Classics, Vol. 1
- Snoopy vs. the Red Baron
- SOCOM - U.S. Navy SEALs - Fireteam Bravo
- SOCOM - U.S. Navy SEALs - Fireteam Bravo 2
- SOCOM - U.S. Navy SEALs - Tactical Strike
- SOCOM - U.S. Navy Seals Fireteam Bravo
- SOCOM - U.S. Navy Seals Fireteam Bravo 2
- SOCOM - U.S. Navy Seals Fireteam Bravo 3
- SOCOM - U.S. Navy Seals Tactical Strike
- Soldier Blade
- Soldier Collection
- Solfege - Sweet Harmony
- Sonic Rivals
- Sonic Rivals 2
- Soukyuu No Fafner
- Soul Calibur - Broken Destiny
- Soul Eater - Battle Resonance
- SoulCalibur - Broken Destiny
- Space Invaders Evolution
- Space Invaders Extreme
- Space Invaders Pocket
- Space Station Tycoon
- Spectral Souls
- Spectral Souls - Resurrection of the Ethereal Empires
- Spectral vs. Generation
- Spelling Challenges and More!
- Spider-Man
- Spider-Man - Freund oder Feind
- Spider-Man - Friend Or Foe
- Spider-Man - Web of Shadows
- Spider-Man 2
- Spider-Man 3
- Spinout
- Splinter Cell - Double Agent
- Splinter Cell - Essentials
- Splinter Cell Essentials
- SpongeBob SquarePants - the Yellow Avenger
- SpongeBob's Truth Or Square
- SSX 4 - On Tour
- SSX On Tour
- Stacked With Daniel Negreanu
- Star Ocean - First Departure
- Star Ocean - Second Evolution
- Star Soldier
- Star Trek - Tactical Assault
- Star Wars - Battlefront - Elite Squadron
- Star Wars - Battlefront - Renegade Squadron
- Star Wars - Battlefront 2
- Star Wars - Lethal Alliance
- Star Wars - Shadow Strike
- Star Wars - the Clone Wars - Republic Heroes
- Star Wars - the Force Unleashed
- Star Wars Battlefront - Renegade Squadron
- Star Wars the Force Unleashed 2
- Steambot Chronicles - Battle Tournament
- Steambot Chronicles - Vehicle Battle Tournament
- Steel Horizon
- Sticky Balls
- STOKED - Freeride Skiing
- Street Fighter Alpha 3 - MAX
- Street Fighter Alpha 3 MAX
- Street Fighter Zero 3 - Double Upper
- Street Supremacy
- Strikers 1945
- Strikers 1945 Plus
- Suigetsu Portable
- Suikoden 1 + 2
- Sunday 10 Magazine - Taisen Action
- Super Collapse 3
- Super Hind
- Super Monkey Ball Adventure
- Super Pocket Tennis
- Super Robot Taisen A Portable
- Super Robot Taisen OE - Operation Extend
- Super Star Soldier
- Super Stardust Portable
- Superbike World Championship 08
- Superman Returns - the Videogame
- Surf's Up
- Suzumiya Haruhi no Yakusoku
- SWAT - Target Liberty
- Syphon Filter
- Syphon Filter - Combat Ops
- Syphon Filter - Dark Mirror
- Syphon Filter - Logan's Shadow