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- Sura Online
- Sure Shot
- Sure Shot 3D
- Surf Ninjas
- Surf's Up
- Surface Tension
- Surfingers
- Surgeon Simulator 2013
- Surgeon Simulator Anniversary Edition
- Surreal
- Survival
- Survival - the Ultimate Challange
- Survival - the Ultimate Challenge
- Survival Kids
- Survivalist
- Survivalist V0.38
- Survivalist V27
- Survivor
- Survivor - the Australian Outback
- Survivor Squad
- Survivor Squad - Gauntlets
- Survivor Squad V1.15
- Survivor the Interactive Game
- Survivors
- Suspect
- Suspects and Clues
- Suspended
- Suzuki Alstare Extrem Racing
- Suzuki Alstare Extreme Racing
- Sven Bomwollen
- Sven Bømwøllen
- Sven Goran Erikssons World Challenge
- Sven kommt
- Sven Zwo
- Sven Zwø
- Sven-Goran Eriksson's World Challenge
- Swap Pop
- Swapper
- Swarm
- Swarm Arena
- Swarm Assault
- Swarm Gold
- Swarm Rampage
- Swarm v1.0
- Swarm v1.4.262
- Swarog
- Swashbucklers - Blue & Grey
- SWAT - Urban Justice
- SWAT 2
- SWAT 3
- Swat 3 - Close Quarters Battle
- SWAT 3 - Close Quarters Battle - Elite Edition
- Swat 3 - Elite Edition
- SWAT 3 Close Quarters Battle Elite Edition
- SWAT 4
- Swat 4 - the Stetchkov Syndicate
- Swedish Saveloy
- Swedish Touring Car Championship 2
- Swedish Touring Cars Championship 2
- Sweet Lily Dreams
- Sweezy Gunner
- Swindle
- Swine
- Swing
- Swipecart
- Switch
- Switch Galaxy Ultra
- Switchbalde
- Switchball
- Switchblade
- Switchfire
- SWIV 3-D
- SWIV 3D
- Sword and the Samurai
- Sword Coast Legends
- Sword Daughter
- Sword of Asumi
- Sword of Honour
- Sword of Sodan
- Sword of the New World - Granado Espada
- Sword of the Samurai
- Sword of the Stars
- Sword of the Stars - A Murder of Crows
- Sword of the Stars - Argos Naval Yard
- Sword of the Stars - Born of Blood
- Sword of the Stars - Collector's Edition
- Sword of the Stars - Ground Pounders
- Sword of the Stars - the Pit
- Sword of the Stars 2 - Lords of Winter
- Sword of the Stars Born of Blood
- Sword of Vermilion
- Swordman
- Swords & Crossbones - An Epic Pirate Story
- Swords & Soldiers
- Swords and Sandals 1
- Swords and Sandals 2 - Emperor's Reign
- Swords and Sandals 3 - Crusader
- Swords and Sandals 3 - Solo Ultratus
- Swords and Soldiers
- Swords and Soldiers HD
- Swords and Sorcery - Underworld - DEFINITIVE EDITION
- Swords of Glass
- Swords of Xeen
- Syberia
- Syberia 2
- Syder Arcade
- Sydney 2000
- Sym
- Symphony
- Syndicate
- Syndicate - American Revolt
- Syndicate (2012)
- Syndicate Plus
- Syndicate Wars
- Syrenka Racer
- Syrnia
- System Protocol One
- System Shock
- System Shock 1
- System Shock 2
- System Shock 2 Co-op Patch
- System Shock 2 Trainer
- System Shock Enhanced Edition