NES - S
- Saint Seiya 2
- Saiyuuki World
- Sanrio Carnival
- Sansara Naga
- Schlümpfe
- SD Splatterhouse
- Secret Scout in the Temple of Demise
- Secret Ties
- Seirei Densetsu Lickle
- Shadow Land
- Shadow of the Ninja
- Shadowgate
- Shadows of the Ninja
- Shanghai
- Shatterhand
- Shingen the Ruler
- Shinobi
- Shockwave
- Shogi Meikan '92
- Shogi Meikan '93
- Silva Saga
- Skate Or Die 2
- Sky Kid
- Smash TV
- Snake, Rattle and Roll
- Snake's Revenge
- Snakes Revenge
- Snow Brothers
- Solar Jetman - Hunt for the Golden Warpship
- Solomons Key
- Solstice
- Somari
- Soreike! Anpanman - Minna de Hiking Game!
- Space Shuttle Project
- Spartan 10 2
- Spiritual Warfare
- Splatterhouse
- Spy Hunter
- Spy vs. Spy
- Stanley
- Stanley - the Search for Dr. Livingston
- Star Tropics
- Star Wars
- Star Wars - the Empire Strikes Back
- StarTropics
- Strider
- Super Bomberman 2
- Super C
- Super Dodge Ball
- Super Glove Ball
- Super Mario Bros
- Super Mario Bros 2
- Super Mario Bros 3
- Super Mario Bros.
- Super Mario Bros. 2
- Super Mario Bros. 3
- Super Mario Brothers
- Super Mario Brothers 2
- Super Mario Brothers 3
- Super Pitfall
- Super Princess Peach
- Super Sprint
- Super Spy Hunter
- Superman
- Sweet Home
- Sword Master
- Swords and Serpents