Game Boy - S
- Sabrina - Zapped!
- Sabrina the Animated Series - Zapped
- Samurai Shodown
- Samurai Shodown 3
- Samurai Showdown 3
- San Francisco Rush 2049
- Schlümpfe im Alptraumland
- Schlümpfe reisen um die Welt
- Scooby-Doo! Classic Creepy Capers
- Scrabble
- Shadow Warriors
- Shadowgate Classic
- Shamus
- Shangai
- Shanghai
- Shanghai Pocket
- Shrek - Fairy Tale FreakDown
- Simpsons - Bart & the Beanstalk
- Simpsons - Bart vs. the Juggernauts
- Simpsons - Treehouse
- Simpsons - Treehouse of Horror
- Simpsons - Treehouse of Terror
- Skate or Die
- Skate or Die - Tour De Thrash
- Slam Dunk 2
- Small Soldiers
- Smurfs
- Smurfs 3
- Smurfs Nightmare
- Smurfs Travel the World
- Smurfs' Nightmare
- Snoopy Tennis
- Snoopy's Magic Show
- Snoopys Magic
- Snow Bros Jr.
- Snow Broth. Junior
- Snow Brothers Jr.
- Soccer
- Soccer Mania
- Solar Strike
- Solitaire FunPak
- Solomon's Club
- Solomons Club T
- Space Invaders
- Space Marauder
- Space Station - Silicon Valley
- Spanky's Quest
- Spankys Quest
- Spawn
- Speedball 2
- Speedball 2 - Brutal Deluxe
- Speedy Gonzales
- Speedy Gonzales - Abenteuer im Atzekenreich
- Speedy Gonzales - Aztec Adventure
- Spider-Man
- Spider-Man 2 - the Sinister Six
- Spider-Man 2 the Sinister Six
- Spirou
- Sponge Bob Squarepants
- SpongeBob SquarePants - Legend of the Lost Spatula
- Sports Illustrated Championship
- Spud's Adventure
- Spy Hunter/Mood Patrol
- Spy Hunter/Moon Patrol
- Spy vs Spy - Operation Boobytrap
- Spy vs. Spy
- Spy vs. Spy - Operation Booby Trap
- Star Trek
- Star Trek - 25th Anniversary
- Star Trek - Generations - Beyond the Nexus
- Star Trek - the Next Generation
- Star Trek Generation
- Star Trek Generations - Beyond the Nexus
- Star Trek NG - Beyond the Nexus
- Star Wars - Battle for Naboo
- Star Wars - Episode 1 - Obi-Wan's Adventures
- Star Wars - Episode 1 - Racer
- Star Wars - Obi-Wan
- Star Wars - Return of the Jedi
- Star Wars - the Empire Strikes Back
- Star Wars - Yoda Stories
- Stranded Kids
- Street Fighter 2
- Street Fighter Alpha - Warriors Dreams
- Street Fighter Alpha - Warriors' Dreams
- Street Fighter Alpha 3
- Street Racer Deluxe
- Stuart Little
- Sumo Fighter
- Super Breakout
- Super Mario Bros Deluxe
- Super Mario Bros. Deluxe
- Super Mario Bros. DX
- Super Mario Brothers DX
- Super Mario Land
- Super Mario Land 1
- Super Mario Land 2
- Super Mario Land 2 - 6 Golden Coins
- Super Mario Land 3
- Super Mario Land 3 - Wario Land
- Super Return of the Jedi
- Super Star Wars - Return of the Jedi
- Superman
- Superman - Countdown to Apokolips
- Supreme Snowboarding
- Survival Kids
- Survival Kids 2
- Swing
- SWIV
- Sword of Hope
- Sword of Hope 2
- Sylvester & Tweety - Vogel zum Frühstück