Game Boy Color - S
- Sabrina -The Animated Series - Zapped
- Sabrina Simsalabim Zapped!
- Sabrina the Animated Series - Zapped!
- Samurai Showdown
- San Francisco Rush 2049
- Schlümpfe im Alptraumland
- Sgt. Rock - On the Frontline
- Shadowgate Classic
- Shamus
- Shaun Palmer's Pro Snowboarder
- Shrek - Fairy Tale FreakDown
- Silvester & Tweety
- Simpsons - Treehouse of Horror
- Simpsons - Treehouse of Terror
- Smurfs Nightmare
- Smurfs' Nightmare
- Snoopy Tennis
- Space Invaders
- Space Marauder
- Spawn
- Speedy Gonzales - Abenteuer im Aztekenreich
- Speedy Gonzales - Aztec Adventure
- Spider-Man
- Spider-Man 2
- Spider-Man 2 - the Sinister Six
- Spider-Man 2 the Sinister Six
- Spirou
- Spirou - the Robot Invasion
- SpongeBob SquarePants - Legend of the Lost Spatula
- SpongeBob SquarePants - Legend/Lost Spatula
- Spy Hunter/Moon Patrol
- Spy vs. Spy
- Star Trek NG - Beyond the Nexus
- Star Wars - Episode 1 - Obi Wan Adventures
- Star Wars - Episode 1 Racer
- Star Wars - Yoda Stories
- Star Wars Episode 1 - Obi-Wan
- Star Wars Episode 1 - Obi-Wan's Adventures
- Star Wars Episode 1 - Racer
- Stranded Kids
- Street Fighter Alpha
- Street Fighter Alpha - Warriors Dreams
- Stuart Little - the Journey Home
- Super Mario Bros.
- Super Mario Bros. Deluxe
- Super Mario Brothers DX
- Supreme Snowboarding
- Survival Kids
- SWiV